REM sleep behaviour disorder
RBD as a prodromal marker, surveillance cohorts and management (melatonin, clonazepam).
State of the art
No update yet for REM sleep behaviour disorder. An update is a standalone state-of-the-art for the topic — what someone with Parkinson's needs to know about where this approach stands today.
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Genome-wide association and population-tailored polygenic risk for Parkinson’s disease in Taiwan
The Taiwan GWAS independently replicates genome-wide significance for rs3756059, a 5′ UTR SNCA variant previously identified in GWAS of REM sleep behaviour disorder (RBD) and PD with RBD, raising the possibility that 5′ SNCA regulatory variation contributes to phenotypic heterogeneity including the RBD prodrome. -
Démence à corps de Lewy : voici pourquoi elle est confondue avec Parkinson et Alzheimer (et ce que ça change) - Cap Retraite
The article describes REM sleep behaviour disorder (physically acting out dreams) as an important early warning sign of LBD that can appear years before cognitive or motor symptoms — framing it as a diagnostic flag for families to bring to their neurologist, particularly when combined with fluctuating alertness or early hallucinations.