PRKN & PINK1
Autosomal-recessive young-onset PD genes and their mitochondrial mechanisms.
State of the art
No update yet for PRKN & PINK1. An update is a standalone state-of-the-art for the topic — what someone with Parkinson's needs to know about where this approach stands today.
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PD GENEration: An International Parkinson's Disease Genetic Research Study
PD GENEration's international dataset — including younger-onset participants enrolled across Latin America — adds diversity to PRKN variant frequency estimates, which were approximately 2.1% in the North American cohort. PRKN is a recessive gene particularly associated with early-onset disease, making it especially relevant for Latin American sites enrolling a younger participant profile.