Picks (written 2026-05-18)
Latest research
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Tolerability and efficacy of full-body head-up tilt sleeping in Parkinson’s disease and multiple system atrophy summary
Head-up tilt sleeping shown tolerable and effective for autonomic symptoms in PD and MSA.
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Levodopa response clarified as prognostic signal distinguishing PD from MSA and PSP.
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Multi-locus genetic dosage shapes cognitive disease progression in Parkinson’s patients: 15-year meta-analysis of 24 cohorts summary
15-year, 24-cohort data links genetic load to individual cognitive decline pace.
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Loneliness predicts worse Parkinsonism: a longitudinal, community-based, clinical-pathological study summary
Loneliness independently predicts worse motor symptoms over time; social connection is modifiable.
News, foundations & community
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Vyalev eases motor, nonmotor symptoms in advanced Parkinson’s summary
Vyalev subcutaneous levodopa infusion cuts off time and nonmotor burden in advanced PD.
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Phase 3 trial of solengepras for Parkinson’s disease now fully enrolled summary
Non-dopaminergic Phase 3 trial fully enrolled; results now on the near horizon.
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Prebiotics balance gut bacteria and show results in Parkinson’s blood summary
Prebiotic supplement restores gut bacteria in PD; progress trackable via blood test.
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New, free Parkinson’s card game aims to help couples rekindle intimacy
Free APDA card game gives couples a concrete tool for intimacy challenges.
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Practical guide to managing overlapping symptoms where PD and menopause intersect.